Abstract
Pituitary adenomas are the third most common benign intracranial tumor seen in neurosurgical
practice. They represent ≥ 15 % of all primary intracranial tumors with 25 % prevalence
as reported in autopsy series. Advances in biomedical assays, imaging studies support
their diagnosis and tailor their management. The direct endonasal transsphenoidal
surgery is the recommended intervention for adenoma resection in more than 95 %. The
safety and efficacy of this intervention was enhanced by microsurgery and more recently
by the introduction of neuronavigation, assisted endoscopy and intraoperative MRI.
Anticipation of clinical, biochemical, radiological and surgical pitfalls by a multidisciplinary
team is of paramount importance in improving treatment and preventing potential complications.
Key words
Pituitary - MRI - hyperplasia - complication - navigation - surgery
